THIS SITE IS INTENDED
FOR US CONSUMERS

  • BEVESPI AEROSPHERE is a prescription medication used long-term to treat adults with COPD READ MORE...(chronic obstructive pulmonary disease), including chronic bronchitis, emphysema, or both. SHOW LESS
  • BEVESPI AEROSPHERE is not a rescue inhaler and is not for use to treat sudden COPD symptoms. READ MORE...It is not for use in asthma. SHOW LESS

ABOUT COPD

WHAT ARE THE STAGES OF COPD?

COPD is a progressive disease that gets worse over time. But it’s important to understand that COPD is not staged the same way as other diseases. Your doctor will consider several factors to determine the severity of your COPD and how to best manage it.

To determine how difficult it is for air to move out of your lungs, your doctor may use a test called spirometry to measure your lung function. You’ll start by taking a deep breath, and then blowing as hard as you can into a machine called a spirometer, which will record measurements like:

  • FEV1 (Forced Expiratory Volume in 1 second), a measure of how much air you can breathe out in 1 second
  • FVC (Forced Vital Capacity), the maximum amount of air you can breathe out in one breath
  • FEV1 /FVC Ratio: FEV1 expressed as a percentage of FVC; people with COPD usually have an FEV1 that is less than 70% of the FVC, or an FEV1 /FVC less than 0.70

Then, based on the degree of your airflow limitation, you may be classified as 1 of 4 GOLD (Global Initiative for Chronic Obstructive Lung Disease) grades. This classification of the severity of reduced airflow in COPD by GOLD is based on FEV1 after using a bronchodilator, in people with FEV1 /FVC less than 0.70:

MILD COPD (GOLD 1)
FEV1 ≥80% predicted
MODERATE COPD (GOLD 2)
50% ≤ FEV1 <80% predicted
SEVERE COPD (GOLD 3)
30% ≤ FEV1 <50% predicted
VERY SEVERE COPD (GOLD 4)
FEV1 <30% predicted

Other factors that your doctor may consider when determining the severity of your COPD are:

icon-breath-shortness YOUR SYMPTOMS, such as breathlessness
icon-activity-level YOUR PHYSICAL ACTIVITY LEVEL, like your ability to walk up the stairs or do activities at home
icon-flare-ups ANY HISTORY OF
FLARE-UPS
(episodes of sudden worsening of your symptoms)
icon-other-factors OTHER FACTORS, such as any other conditions you might have

icon-checklist

To understand how COPD symptoms may affect you, ask your doctor any questions you might have.

USE THIS DISCUSSION GUIDE TOP

IMPORTANT SAFETY INFORMATION ABOUT BEVESPI AEROSPHERE INCLUDING BOXED WARNING

People with asthma who take long-acting beta2-adrenergic agonist (LABA) medicines, such as formoterol fumarate (one of the medicines in BEVESPI AEROSPHERE), have an increased risk of death from asthma problems. It is not known if LABA medicines increase the risk of death in people with COPD. BEVESPI AEROSPHERE is only approved for use in COPD. BEVESPI AEROSPHERE is not approved for use in asthma.

  • Call your healthcare provider if breathing problems worsen over time while using BEVESPI AEROSPHERE
  • Get emergency medical care if your breathing problems worsen quickly or if you use your rescue inhaler, but it does not relieve your breathing problems
  • Do not use BEVESPI AEROSPHERE to treat sudden symptoms of COPD. Always have a rescue inhaler with you to treat sudden symptoms
  • BEVESPI AEROSPHERE is not for the treatment of asthma. It is not known if BEVESPI AEROSPHERE is safe and effective in people with asthma
  • Do not use BEVESPI AEROSPHERE if you are allergic to glycopyrrolate, formoterol fumarate, or to any of the ingredients in BEVESPI AEROSPHERE
  • Do not use BEVESPI AEROSPHERE more often than prescribed
  • Do not take BEVESPI AEROSPHERE with other medicines that contain a LABA or an anticholinergic for any reason. Tell your healthcare provider about all the medicines you take
  • Tell your healthcare provider about all your medical conditions including heart problems, high blood pressure, seizures, thyroid problems, diabetes, liver problems, glaucoma, prostate or bladder problems, or problems passing urine

BEVESPI AEROSPHERE can cause serious side effects, including:

  • Sudden breathing problems immediately after inhaling your medicine
  • Serious allergic reactions. Call your healthcare provider or get emergency medical care if you get any of the following symptoms of a serious allergic reaction: rash; hives; swelling of the face, mouth and tongue; breathing problems
  • Fast or irregular heartbeat, increased blood pressure, chest pain
  • Tremor or nervousness
  • New or worsened eye problems, including acute narrow-angle glaucoma. Symptoms may include: eye pain or discomfort, nausea or vomiting, blurred vision, seeing halos or bright colors around lights, and red eyes. If you have these symptoms, call your healthcare provider right away before taking another dose
  • New or worsened urinary retention. Symptoms may include difficulty urinating, painful urination, urinating frequently, or urinating in a weak stream or drips. If you have any of these symptoms, stop taking BEVESPI AEROSPHERE and call your healthcare provider right away
  • High blood sugar or low blood potassium

Common side effects of BEVESPI AEROSPHERE include urinary tract infection and cough. Tell your healthcare provider about any side effect that bothers you or that does not go away.

APPROVED USE

BEVESPI AEROSPHERE is a prescription medicine used to treat chronic obstructive pulmonary disease (COPD). COPD includes chronic bronchitis, emphysema, or both. BEVESPI AEROSPHERE is used long term as 2 inhalations, 2 times each day in the morning and in the evening, to improve symptoms of COPD for better breathing. Do not use BEVESPI AEROSPHERE to treat sudden symptoms of COPD; it won't replace a rescue inhaler. BEVESPI AEROSPHERE is not for the treatment of asthma.

Please read full Prescribing Information , including Boxed WARNING, and Medication Guide and Instructions for Use for BEVESPI AEROSPHERE.

IMPORTANT SAFETY INFORMATION ABOUT BEVESPI AEROSPHERE INCLUDING BOXED WARNING

People with asthma who take long-acting beta2-adrenergic agonist (LABA) medicines, such as formoterol fumarate (one of the medicines in BEVESPI AEROSPHERE), have an increased risk of death from asthma problems. It is not known if LABA medicines increase the risk of death in people with COPD.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.FDA.gov/medwatch or call 1-800-FDA-1088.1-800-FDA-1088.

USA flagThis site is intended for US Consumers only.

The information on this Web site should not take the place of talking with your doctor or health care professional. If you have any questions about your condition, or if you would like more information about BEVESPI AEROSPHERE or COPD, talk to your doctor or pharmacist. Only you and your doctor can decide if BEVESPI AEROSPHERE is right for you.